PReAcT

Identifying Predictive Factors for the Recovery of Achilles Tendinopathy (PReAcT trial)

This project aims to identify psychosocial and metabolic factors influencing the recovery of Achilles tendinopathy (AT) through a longitudinal cohort study

Understanding Achilles Tendinopathy Recovery

Achilles tendinopathy (AT) can lead to chronic pain and disability, significantly impacting patients' quality of life. Management of AT is challenging with approximately 50% responding to standard treatment options. Recent studies implicate that both individuals with a metabolic disease and having psychosocial problems will have a worse prognosis of AT. This project investigates in-depth predictive psychosocial and metabolic factors that influence recovery, aiming to develop a clinical classification model for improved patient management.

Innovative Research Approach

We conduct a longitudinal cohort study to assess patient recovery using clinical assessments, proteomic analysis, and psychosocial evaluations. Our research integrates patient-reported outcomes with objective biomarkers to establish a comprehensive prognostic model.

Collaboration and Impact

This project is conducted at Erasmus MC in collaboration with leading experts in musculoskeletal research and proteomics. The findings will support the development of a person-centered treatment protocol to improve rehabilitation strategies for AT patients.
 

Funds & Grants

Marie Skłodowska-Curie Actions (MSCA) - Postdoctoral Fellowship

Collaboration: 

Vrije Universiteit Brussel (VUB): Wouter van Bogaert

University Hospital
Rotterdam Study (Erasmus MC cohort study)