HIPSTAR

Hip dysplasia is the most prevalent risk factor for hip osteoarthritis (OA) in younger generation, a degenerative condition that causes pain, stiffness, and disability in the hip joint. Hip OA is incurable and often requires joint replacement surgery, which is traumatic and costly

The existing classifications of hip dysplasia are mainly based on radiological measurements of the hip joint, such as the center-edge angle, the acetabular index, and the Tönnis grade. However, these classifications do not capture the diversity and complexity of hip dysplasia, nor do they account for the delivery position, genetic, and biomechanical factors that may have a significant impact on its development and progression.

This research aims to identify different phenotypes of the period from infant to adolescent hip dysplasia based on the 5D hip joint growth data from the Generation R project or other renowned cohort The Rotterdam Study project and to assess whether they have underlying mechanisms and potential trajectories.  
 

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