Osteoarthritis is a progressive and degenerative disease of the joints that causes impaired mobility and pain. It affects all joint tissues: cartilage, bone, synovium, tendons and ligaments. How these changes are orchestrated is not fully understood. We currently have no cure for osteoarthritis. At the end stage, joint replacement surgery is the main treatment option. By gaining more insight in osteoarthritis etiology, we aim to develop new treatments that can prevent the development of OA or delay the need for joint replacement surgery.
- Study early phases of osteoarthritis to stop progression to chronic end-stage osteoarthritis or reverse this process
- Improve the surgical and non-surgical treatment of OA
- Develop new biological treatment methods
- Develop methods for the early-stage recognition of OA